Re: "Man, I wish I could take that back"
I work for a big organization.
Possibly the most important career lesson I've learned is to know (1) who used to sleep together, (2) who is currently sleeping together, and (3) who wants to sleep together.
(Sleep, of course, being a euphemism for other types of adult activity.)
I've had a couple of situations where I've said something to the effect of "she's an odd bird", only to find out that someone pretty senior in the organization was, uh, indulging himself.