Re: 125 pitches??!!
I think it's more of a question of risk. Even if there's a just 1% chance that he'd do some damage by throwing 15-20 more pitches than most of would like, why take it?
Games are won on run differential -- scoring more than your opponent. Runs are runs, scored or prevented they all count the same. Worry about scoring more and allowing fewer, not which positions contribute to which side of the equation or how "consistent" you are at your current level of performance.