Victor Von Doom isn't really a villain, exactly. He has two goals: save his dead mother from Hell and save the world from itself. Now he is very egotistical and believes the only way to save the earth is for him to rule it.
He hates Reed Richards, kind of, but he is Valerie Richards' godfather.
Worst thing Doom ever did was stiffing Luke Cage for $200 (sweet Christmas!)
Lex Luther, however, is all bad.
"But I do know Joey's sister indirectly (or foster sister) and I have heard stories of Joey being into shopping, designer wear, fancy coffees, and pedicures."