This is not tied to any genre ...

1. Arular; M.I.A.
2. Picaresque; The Decemberists
3. The Life Aquatic with Steve Zissou soundtrack
4. Exploration; Sarah Lee Guthrie & Johnny Irion
5. The Origin of Fire: Music and Visions of Hildegard von Bingen; Anonymous 4
6. Guero; Beck
7. Get Behind Me Satan; The White Stripes
8. Radiance (Live); Keith Jarrett
9. Awake is the New Sleep; Ben Lee
10. The Light in the Piazza (2005 Original Broadway Cast)
11. Essex Hideaway; Kimberley Rew
12. Forever Hasn't Happened Yet; John Doe
13. Here Comes the ABCs; They Might be Giants
14. End of Love; Clem Snide
15. Let it Die; Feist
16: Martha Wainwright; Martha Wainwright
17. Face the Truth; Stephen Malkmus
18. The Woods; Sleater-Kinney
19. Chavez Ravine; Ry Cooder
20. Naturally; Sharon Jones and the Dap-Kings
21. Calcutta Slide-Guitar, Vol. 3; Debashish Bhattacharya
22. Black Sheep Boy; Okkervil River
23. Brazilian Girls; Brazilian Girls
24. The Tigers Have Spoken (Live); Neko Case
25. X&Y; Coldplay
26. I am a Bird Now; Antony and the Johnsons
27. The Duhks; The Duhks
28. Richard Goode Performs Mozart
29. Rive Gauche Rio; Celso Fonseca
30. Separation Sunday; The Hold Steady
31. Gimme Fiction; Spoon
32. Aha Shake Heartbreak; Kings of Leon
33. The Sunset Tree; The Mountain Goats
34. Elevator; Hot Hot Heat
35. Set Yourself on Fire; Stars
36. Motifs; Paris Combo
37. Hotel Rwanda soundtrack
38. Ragin' Live (live); Rhonda Vincent & the Rage
39. Sound Unity; William Parker Quartet
40. Employment; Kaiser Chiefs
41. Waiting for the Sirens' Call; New Order
42. Mezmerize; System of a Down
43. Shifting Gears; Z-Trip
44. Humming by the Flowerd Vine; Laura Cantrell
45. Happy Doing What We're Doing; Elizabeth McQueen & the Firebrands
46. The Forgotten Arm; Aimee Man
47. The Great Destroyer; Low
48. The Grateful Dead Movie Soundtrack
49. Jumping the Creek; Charles Lloyd
50. Make Believe (Dig); Weezer

Here's the link to the top 50

Honorable mentions