I used Dusty's Official opening day lineup, and I ran Baseball Musings Lineup Analysis tool.

My lineup is...
Votto, Joey
Keppinger, Jeff
Dunn, Adam
Encarnacion, Edwin
Griffey Jr., Ken
Phillips, Brandon
Bruce, Jay
Valentin, Javier
Pitcher 2007

Pitcher 2007 = Reds pitching stats from 2007....

I used MLB.COM Composite Projections. These are 7 different projections from various sources including some of the elite.

Here are the results...
Dusty - Runs per game for above lineup: 4.673.
Me - Runs per game for above lineup: 4.931.

Dusty - 757 Runs Scored
Me - 799 Runs Scored
Last Year - 783 Runs Scored

So basically 42 Runs = about 4 Wins. Lineup construction alone could cost 4 Wins. That's a HUGE difference.