Good little stat here from Gammons:
3. Pitching efficiency is a wonderful thing. Players love pitchers who get one-pitch outs. I believe Greg Maddux once said a perfect game is 27 pitches, 27 outs.
Cliff Lee leads the majors in one-pitch outs with 45, which tells us that had the Indians played better defense, his record would be considerably better. Aaron Harang and Zach Duke are next with 41, while Jon Garland (4.0), Harang (4.0), Lee (3.9) and Glen Perkins (3.9) are the first-pitch strikes per nine innings leaders.