You're not even talking about the same study. The study was Extended-Release Niacin vs. Ezetimibe. It was the ARBITER 6-HALTS study and appears in the New England Journal of Medicine.I am no Zetia drug rep, but the study that I saw about Zetia didn't say it was ineffective, it said that the combo of Zetia and simvastatin (Vytorin) was no more effective than simvastatin alone.(And this was only one study). I'd appreciate a link to the journal article you have on the overall ineffectiveness of ezetimibe.
I'd be interested to read the article and would like to bring it to the attention of my professor who said extended-release was not as effective. Does the article mention anything about the potential hepatotoxicity of extended-release niacin?
I'll get on Medline after exams and try to find the article.
So far I've had trouble with every statin I've taken, and I start to feel it first in the joints of my fingers. (Clarification, I've got arthritic issues and have both Bouchard's and Heberden's nodes) This continues to the point where my hands are very stiff and painful to the point of where I can't type, hardly move them, and it begins to impact my livelhood, etc... I've talked with my rheumatologist and my gp concerning it and they both just kind of go hmmmm.....
Was wondering if any of the vast resources here might have any insight?????????
I've been on Zetia about 3 days, and my hands feel very stiff this morning, (not a 10th as bad as when I was on Zocor) but we also have some major frontal activity in my area today so the jury is still out and I'll continue to monitor it as I continue to take it.
In those things which we commit to practice we can master, and with mastery we have the freedom to use these skills whenever we desire, without this practice we are slaves to our inability.