Without a light rail infrastructure in each city, I don't see myself using this a whole lot. I might take the train to Cincinnati from Columbus (as I work downtown) to see the Reds, but I really couldn't get elsewhere I'd want to go (like Mt. Healthy) in Cincy without taking the bus. I certainly wouldn't take the train into downtown Dayton and then a bus to where I'd want to go; I'd just drive and be there in 50-55 minutes instead.
The only place in Ohio this would really work is Cleveland, as they already have good light rail. I would take the train to Puritas station and then jump on the red line downtown.